Kill 6 Billion Demons: Sorority sister fights through the demon realm(s) to rescue her boyfriend. She’s not actually that into the boyfriend — in fact, she’ll hook up with a quirky, pointy demon lady along the way — but she’s the only human who even knows where she is, so it’s up to her.

Weird and involved monster/creature designs, absolutely amazing settings. I’ve saved so many pages because things like “long shot of a marketplace built in the stone head of a petrified dead god” make great inspiration.

The Hazards of Love: Queer teen who obviously never watched Madoka Magica makes a deal with a talking cat, gets stuck in a monster dimension, but this one doesn’t fight battles so much as “do housework for an evil shadow deer.” Their girlfriend starts to suspect something is up, but the only other beings in Queens who know what really happened are ghosts, so that’s going to be tough.

Bright World’s aesthetic comes from the Mexican ephemera the artist grew up with, which isn’t a flavor you see in a lot of webcomic settings. The online version is black-and-white — pick up the books to see it in color.

Devil’s Candy: Cute imp student makes a Frankenstein girl for a science project. Hijinks ensue.

No alternate human dimension in this one — it’s just a monster school, with cool goth architecture, fun culture clashes, and cute kids dealing with struggles like “as a mixed-species monster, how do I balance the expectations from both sides of my family?” and “how do I get my designs through this fashion show alive?”

Girl Genius: In a steampunk alternate Europe governed by mad scientists, Agatha learns she has massive talents as the heir to a brilliant family’s legacy, all suppressed for her protection. Until now.

An amazing study in payoffs for long-term setup — someone tries to invite Agatha to England around book 2 or 3, she accepts the invitation around book 20. (Which is when we find out London is a network of submarine domes, run by a giant shapeshifter.)

The Last Halloween: Trick-or-treating is canceled, the monsters are invading. To find out what’s going on (and, hopefully, how to fix it), Mona teams up with some other kids she assumes are just in their costumes already…

Only comic on this list that’s fully set in the Real World, since it explores how that world gets permanently changed. Always suspenseful, sometimes pretty gruesome, usually funny anyway.

Bruno the Bandit: Sword and sorcery (and cell phones…and social satire) with a selfish mercenary and his put-upon microdragon sidekick. Their struggles include Lovecraftian horrors, fame vampires, and losing the TV remote.

Honestly, this is the series that most inspired the “off-color jokes that seem very dated” warning. But they usually come from characters that aren’t supposed to be guiding lights of moral clarity, and the comic’s best moments are timelessly on-point.

…it also has some surprisingly-direct inspiration for things I ended up putting in Leif & Thorn.

Dreamless: A romantic drama about two people on opposite sides of the world — he’s in Japan, she’s in the US — who see each other’s waking lives while they’re asleep. Then WWII breaks out.

The art in this one might not stand out in the modern-day webcomic scene, but when it launched? This level of painterly, realistic style — for an internet comic! — was kind of mind-blowing.

User Friendly: Misadventures of a bunch of geeks employed by a programming company. Like Dilbert, but in the good ways, not the “weird authorial MRA spiral” ways.

Honestly, I have no idea if this will be funny or relatable to new readers who weren’t around for the era of nerd culture it’s riffing on. But maybe it will! Give it a try, let me know.

Ozy and Millie: Two best friends, an introspective wolf and an energetic chaos-agent fox, have cute adventures. Some philosophy, some politics, one excellent dragon dad.

The artist got wildly popular later on for Phoebe And Her Unicorn. I wish that translated into more appreciation for her early work! It’s not like her skills were undercooked back when she drew this series — it absolutely shines.

Suburban Jungle: Furry sitcom adventures (with a dash of sci-fi) of model and would-be actress Tiffany Tiger, and her friends and colleagues around LA.

If you click with it, check out the sequel series too. (Maybe even check out the sequel if you don’t click with it! Same universe, but the artist tries new things.)